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利用核DNA多态性对三个美洲印第安人群体进行的研究。

Studies of three Amerindian populations using nuclear DNA polymorphisms.

作者信息

Kidd J R, Black F L, Weiss K M, Balazs I, Kidd K K

机构信息

Department of Human Genetics, Yale University School of Medicine, New Haven, CT 06510.

出版信息

Hum Biol. 1991 Dec;63(6):775-94.

PMID:1683642
Abstract

Three Amerindian populations, two from Rondônia, Brazil (Karitiana and Rondônia Suruí), and one from Campeche, Mexico (Mayan), were typed for up to 30 nuclear restriction fragment length polymorphisms (RFLPs). Heterozygosities, both observed and expected, were compared with those of Europeans. Average heterozygosity is reduced among these Amerindians (relative to that of Europeans) by 7.0% (Mayan) to 27.1% (Karitiana). This amount of heterozygosity in the nuclear DNA is nevertheless high enough that it is unlikely that there was a severe or prolonged bottleneck.

摘要

对三个美洲印第安人群体进行了多达30种核限制性片段长度多态性(RFLP)分型,其中两个群体来自巴西朗多尼亚州(卡里蒂亚纳人和朗多尼亚苏鲁人),一个群体来自墨西哥坎佩切州(玛雅人)。将观察到的和预期的杂合度与欧洲人的杂合度进行了比较。这些美洲印第安人的平均杂合度(相对于欧洲人)降低了7.0%(玛雅人)至27.1%(卡里蒂亚纳人)。然而,核DNA中的这种杂合度水平仍然足够高,不太可能存在严重或长期的瓶颈效应。

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