南美人群中F13B基因座的变异性。

Variability of the F13B locus in South American populations.

作者信息

Tourret M N, Catanesi C I, Vidal-Rioja L

机构信息

Laboratorio de Identificación Genética, Instituto Multidisciplinario de Biología Celular, La Plata, Argentina.

出版信息

Hum Biol. 2000 Aug;72(4):707-14.

PMID:11048796

Abstract

A population study for the F13B locus was carried out in a total of 396 South American individuals. The analysis comprised new data from 5 Amerindian populations, existing data from 3 Amerindian populations, and I urban sample from La Plata, Argentina. In both pooled Amerindian and La Plata samples, 6 alleles were found. The individual Amerindian samples showed a lower number of alleles, changes in modal alleles, and restricted variability. Interpopulation comparisons revealed significant differences among samples from distinct geographical regions. Differences among the groups were also corroborated by the F(ST) statistic. Data support the hypothesis that genetic drift and gene flow influence Amerindian differentiation.

摘要

对F13B基因座进行了一项群体研究，共涉及396名南美个体。分析包括来自5个美洲印第安人群体的新数据、来自3个美洲印第安人群体的现有数据，以及来自阿根廷拉普拉塔的1个城市样本。在合并的美洲印第安人和拉普拉塔样本中，发现了6个等位基因。各个美洲印第安人样本显示出较低的等位基因数量、模式等位基因的变化以及有限的变异性。群体间比较揭示了来自不同地理区域的样本之间存在显著差异。F(ST)统计量也证实了各群体之间的差异。数据支持遗传漂变和基因流影响美洲印第安人分化的假说。