肺膨胀对通过电导法测量绝对心室容积的影响。

The effect of lung inflation on absolute ventricular volume measurement by conductance.

作者信息

Haney Michael F, Steendijk Paul, Johansson Göran, Biber Björn

机构信息

Surgical and Perioperative Sciences, Anesthesiology and Intensive Care Medicine, Umeå University Hospital, Sweden.

出版信息

Clin Physiol Funct Imaging. 2006 Jul;26(4):220-3. doi: 10.1111/j.1475-097X.2006.00681.x.

DOI:10.1111/j.1475-097X.2006.00681.x

PMID:16836694

Abstract

BACKGROUND

Conductance catheter in vivo ventricular volume measurements during lung ventilation may provide important information on left ventricular (LV) function. Breathing potentially may alter parallel conductance (V(c)), complicating interpretation of the conductance-derived volume signals. The effects of controlled positive pressure lung inflation (PPLI) on measured parallel conductance with dual-field conductance volumetry were investigated.

METHODS

Eight anaesthetized pigs were instrumented with an LV dual-field conductance volumetry catheter. V(c) was measured repeatedly, using the hypertonic saline injection method, at three different levels of lung insufflation: continuous positive airway pressure (PPLI) 0, 5, and 10 cm H(2)O.

RESULTS

V(c)s measured at PPLI 0, 5 and 10 cm H(2)O were 70.9 +/- 4.8, 70.7 +/- 5.5 and 70.5 +/- 5.9 ml, respectively. The corresponding uncalibrated end-diastolic volumes (EDV(u)) were 115.5 +/- 7.1, 117.0 +/- 7.5 and 117.5 +/- 7.7 ml, respectively. Mean coefficients of variance for V(c) and EDV(u) at all three PPLI levels were 3.8% and 1.25%, respectively.

DISCUSSION

Several levels of PPLI demonstrated no systematic change in parallel conductance for LV dual-field conductance volume signal. We concluded that lung inflation at these levels does not generate changes in V(c).

摘要

背景

在肺通气期间使用电导导管进行体内心室容积测量可能会提供有关左心室（LV）功能的重要信息。呼吸可能会改变平行电导（V(c)），使从电导得出的容积信号的解释变得复杂。本研究调查了控制性正压肺充气（PPLI）对双场电导容积法测量的平行电导的影响。

方法

对八只麻醉猪植入左心室双场电导容积测量导管。使用高渗盐水注射法，在三种不同的肺充气水平下重复测量V(c)：持续气道正压（PPLI）0、5和10 cm H₂O。

结果

在PPLI 0、5和10 cm H₂O水平下测量的V(c)分别为70.9±4.8、70.7±5.5和70.5±5.9 ml。相应的未校准舒张末期容积（EDV(u)）分别为115.5±7.1、117.0±7.5和117.5±7.7 ml。在所有三个PPLI水平下，V(c)和EDV(u)的平均变异系数分别为3.8%和1.25%。