Hanssen Imke, van der Horst Nicole, Boele Marieke, Lochmann van Bennekom Marc, Regeer Eline, Speckens Anne
Radboud University Medical Centre, Department of Psychiatry, Centre for Mindfulness, Postbus 9101, 6500 HB, Nijmegen, The Netherlands.
Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, The Netherlands.
Int J Bipolar Disord. 2020 Nov 11;8(1):33. doi: 10.1186/s40345-020-00197-y.
Mindfulness- Based Cognitive Therapy (MBCT) could be a promising psychosocial intervention for people with bipolar disorder (BD). However, little is known about the feasibility of MBCT for people with BD. In this study we explore the facilitators and barriers people with BD experience of an adapted MBCT program.
This qualitative study is part of a large, multicenter randomized controlled trial on MBCT for BD (trial registration number: NCT03507647). The present study included 16 participants with BD who participated in an 8-week adapted MBCT program. Semi- structured interviews exploring the feasibility, with a particular focus on the bipolar symptoms, were recorded verbatim, transcribed and analyzed. For reasons of triangulation, teachers were interviewed as well.
Participants reported different barriers and facilitators of MBCT, both generally as well as with regard to their bipolar disorder. Four key themes arose: the training itself, psychosocial factors, personal characteristics and the bipolar disorder. Themes were further divided in subthemes.
The adapted MBCT program seemed to be feasible for people with BD. Depressive symptoms often acted as a barrier for participating in MBCT, suggesting that participants might need additional support when depressed. Manic symptoms could act both as a barrier and facilitator, suggesting that the occurrence of (hypo)mania does not necessarily have to be an exclusion criterion for participation. Further clinical and research implications are suggested.
ClinicalTrials.gov, NCT03507647. Registered 25th of April 2018, https://clinicaltrials.gov/ct2/show/NCT03507647 .
基于正念的认知疗法（MBCT）可能是一种对双相情感障碍（BD）患者有前景的社会心理干预方法。然而，对于BD患者而言，MBCT的可行性知之甚少。在本研究中，我们探讨了BD患者在接受适应性MBCT项目过程中所经历的促进因素和障碍。
本定性研究是一项关于BD的MBCT大型多中心随机对照试验的一部分（试验注册号：NCT03507647）。本研究纳入了16名BD患者，他们参加了为期8周的适应性MBCT项目。对探索可行性的半结构化访谈进行了逐字记录、转录和分析，访谈特别关注双相症状。出于三角验证的原因，还对教师进行了访谈。
参与者报告了MBCT在总体上以及与双相情感障碍相关方面的不同障碍和促进因素。出现了四个关键主题：培训本身、社会心理因素、个人特征和双相情感障碍。这些主题进一步细分为子主题。
适应性MBCT项目对BD患者似乎是可行的。抑郁症状常常成为参与MBCT的障碍，这表明参与者在抑郁时可能需要额外的支持。躁狂症状既可能是障碍也可能是促进因素，这表明（轻）躁狂的发作不一定必须成为参与的排除标准。文中还提出了进一步的临床和研究意义。
ClinicalTrials.gov，NCT03507647。于2018年4月25日注册，https://clinicaltrials.gov/ct2/show/NCT03507647 。
