心肌梗死中的自身免疫
Autoimmunity in myocardial infarction.
作者信息
Liao Yu-Hua, Cheng Xiang
机构信息
Laboratory of Cardiovascular Immunology, Institute of Cardiology, Union Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430022, China.
出版信息
Int J Cardiol. 2006 Sep 10;112(1):21-6. doi: 10.1016/j.ijcard.2006.05.009. Epub 2006 Jul 11.
Myocardial infarction is associated with an immune response. Physiological inflammation response causes self-repair and protection, while pathological autoimmune response leads to ventricular remodeling and heart failure. Laying emphasis on regulating the immune function may become a new target for the prevention of heart failure after myocardial infarction. This review focuses on the mechanism of immune-mediated ventricular remodeling and the immune therapy after myocardial infarction.
心肌梗死与免疫反应相关。生理性炎症反应可引起自我修复和保护，而病理性自身免疫反应则会导致心室重构和心力衰竭。重视调节免疫功能可能成为预防心肌梗死后心力衰竭的新靶点。本综述聚焦于免疫介导的心室重构机制及心肌梗死后的免疫治疗。
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