Na Sun Hee, Jin Seung-Hyun, Kim Soo Yong
Department of Physics, Korea Advanced Institute of Science and Technology, Daejeon, Korea.
Int J Psychophysiol. 2006 Nov;62(2):238-42. doi: 10.1016/j.ijpsycho.2006.03.006. Epub 2006 Jul 11.
Sleep deprivation can affect the waking electroencephalogram (EEG) that may reflect functional organization of the brain. We examined the effect of total sleep deprivation (TSD) on functional organization between different cortical areas from the waking EEG. Waking EEG data were recorded from 18 healthy male volunteers with eyes closed after 8-h night's sleep and after 24 h of TSD. The averaged cross mutual information (A-CMI) after 24 h of TSD were compared to before TSD. 24 h of TSD yielded the decreased A-CMIs in the inter-hemispheric C3-F4, C3-F8, and C3-C4 pairs: therefore, the electrodes that contribute to pairs with significant decrease of A-CMI were C3, F4, F8, and C4. The decreased A-CMIs between C3 and right frontal and central brain areas after 24 h of TSD may reflect the changes of cortico-cortical functional organization by homeostatic process during TSD. Our results of the frontal-area-related A-CMI decreases may support that the frontal brain regions are related to the homeostatic deterioration of brain function due to TSD.
睡眠剥夺会影响清醒时的脑电图（EEG），而脑电图可能反映大脑的功能组织。我们从清醒脑电图研究了完全睡眠剥夺（TSD）对不同皮质区域之间功能组织的影响。从18名健康男性志愿者身上记录了清醒脑电图数据，分别在8小时夜间睡眠后以及24小时完全睡眠剥夺后闭眼状态下进行记录。将24小时完全睡眠剥夺后的平均交叉互信息（A-CMI）与完全睡眠剥夺前进行比较。24小时完全睡眠剥夺导致半球间C3-F4、C3-F8和C3-C4导联对的A-CMI降低；因此，导致A-CMI显著降低的导联对中的电极分别为C3、F4、F8和C4。24小时完全睡眠剥夺后C3与右侧额叶和中央脑区之间A-CMI的降低可能反映了完全睡眠剥夺期间通过稳态过程引起的皮质-皮质功能组织的变化。我们关于额叶区域相关A-CMI降低的结果可能支持额叶脑区与完全睡眠剥夺导致的脑功能稳态恶化有关这一观点。
