Jeong J, Kim D J, Kim S Y, Chae J H, Go H J, Kim K S
Department of Diagnostic Radiology and Child Study Center, School of Medicine, Yale University CT, 06520-8042, USA.
Sleep. 2001 Mar 15;24(2):197-202.
Sleep deprivation can affect the waking EEG that may reflect information processing of the brain. We examined the effect of total sleep deprivation (TSD) on nonlinear dynamics of the waking EEG.
Paired-group design.
A sleep disorders laboratory in a hospital.
Twenty healthy male volunteers.
Waking EEG data were recorded from subjects with eyes closed after (a) an 8-hour night's sleep and (b) TSD for 24 hours. The dimensional complexity (D2), as a nonlinear measure of complexity, of the EEG after a full night sleep were compared with those of the EEG after TSD.
The sleep-deprived states had lower D2 values at three channels (P4, O2, and C3) than normal states.
TSD results in the decrease of complexity in the brain, which may imply sub-optimal information processing of the cerebral cortex. We suggest that the investigation of the relation between nonlinear dynamics of the waking EEG induced by TSD and cognitive performance may offer fruitful clues for understanding the role of sleep and the effects of sleep deprivation on brain function.
睡眠剥夺会影响清醒时的脑电图，这可能反映大脑的信息处理情况。我们研究了完全睡眠剥夺（TSD）对清醒脑电图非线性动力学的影响。
配对组设计。
一家医院的睡眠障碍实验室。
20名健康男性志愿者。
在（a）8小时夜间睡眠后和（b）24小时TSD后，记录受试者闭眼时的清醒脑电图数据。将整夜睡眠后脑电图的维度复杂性（D2，一种复杂性的非线性度量）与TSD后脑电图的维度复杂性进行比较。
在三个通道（P4、O2和C3）上，睡眠剥夺状态的D2值低于正常状态。
TSD导致大脑复杂性降低，这可能意味着大脑皮层的信息处理未达到最佳状态。我们认为，研究TSD引起的清醒脑电图非线性动力学与认知表现之间的关系，可能为理解睡眠的作用以及睡眠剥夺对脑功能的影响提供丰富的线索。
