Hiraki Akio, Murakami Tomoyuki, Aoe Keisuke, Matsuda Eisuke, Maeda Tadashi, Uemori Yoshiki, Ueoka Hiroshi
Department of Respiratory Medicine, NHO Sanyo National Hospital, Respiratory Disease Center, Ube, Yamaguchi 755-0241, Japan.
Acta Med Okayama. 2006 Jun;60(3):197-200. doi: 10.18926/AMO/30750.
We describe here a patient with a recurrent hemangiopericytoma of the superior mediastinum 23 years after an initial complete resection. In the current biopsy specimen, the tumor cells were much more anaplastic than those seen 23 years ago. Although the patient was treated with chemotherapy, which consisted of ifosfamide and epirubicin, the tumor was unresponsive and he died 6 months later from disease progression. Careful long-term follow-up is mandatory for patients with hemangiopericytomas because recurrence with greater malignancy can develop following an extended disease-free interval.
我们在此描述一名患者，其在首次完全切除23年后出现了复发性上纵隔血管外皮细胞瘤。在当前的活检标本中，肿瘤细胞的间变程度比23年前所见的细胞要高得多。尽管该患者接受了由异环磷酰胺和表柔比星组成的化疗，但肿瘤无反应，患者6个月后因疾病进展而死亡。对于血管外皮细胞瘤患者，必须进行仔细的长期随访，因为在较长的无病间隔期后可能会出现恶性程度更高的复发情况。
