de Saussure P, Chofflon M, Pugin P, Bierens de Hahn D, Perrin L
Laboratoire central de sérologie virale, Hôpital cantonal universitaire de Genève.
Schweiz Med Wochenschr. 1991 Nov 30;121(48):1761-6.
HTLV-I/II (human T-cell lymphotropic virus type I and II) infection is endemic in South Japan, Subsaharan Africa, the Caribbean and in regions of South America and of the United States. The infection almost always remains asymptomatic but is also associated with two distinct diseases: tropical spastic paraparesis (TSP), and adult T-cell leukemia (ATL). Although very rare in Europe, HTLV-I/II infection may occur in patients originating from endemic areas. We report the cases of four patients seropositive for HTLV-I/II, all of them living in Switzerland. Three of them originate from Zaire; the fourth is a Swiss female married to a Taiwanese. One patient has TSP; one has pyramidal signs along with systemic vasculitis-associated neuropathy; the third is HIV-position with stage III B infection, without symptoms of TSP or ATL; the last is entirely asymptomatic.
人类嗜T淋巴细胞病毒I型和II型（HTLV-I/II）感染在日本南部、撒哈拉以南非洲、加勒比地区以及南美洲和美国的部分地区呈地方性流行。这种感染几乎总是无症状的，但也与两种不同的疾病相关：热带痉挛性截瘫（TSP）和成人T细胞白血病（ATL）。虽然在欧洲非常罕见，但HTLV-I/II感染可能发生在来自流行地区的患者中。我们报告了4例HTLV-I/II血清学阳性患者的病例，他们均居住在瑞士。其中3例来自扎伊尔；第4例是一名与台湾人结婚的瑞士女性。1例患者患有TSP；1例有锥体束征以及与系统性血管炎相关的神经病变；第3例HIV阳性，处于III B期感染，无TSP或ATL症状；最后1例完全无症状。
