Effects of corticoliberin fragment CRF(4-6) on sexual behavior in male rats [corrected].
作者信息
Andreev-Andrievskii A A, Tsvirkun D V, Makarenko E Yu, Andreeva L A, Mart'yanov A A
机构信息
M. V. Lomonosov Moscow State University, Vorob'evy Gory, 119992 Moscow, Russia.
出版信息
Neurosci Behav Physiol. 2006 Sep;36(7):755-8. doi: 10.1007/s11055-006-0084-y.
PMID:16841157
Abstract
Centrally administered doses of the tripeptide corticoliberin fragment CRF(4-6) (Pro-Pro-Ile) suppressed mating behavior in male rats. Doses of 1 and 2 microg of the tripeptide produced dose-dependent increases in the latent periods of mounting, intromission, and ejaculation. Changes in measures of sexual behavior demonstrated that the corticoliberin fragment CRF(4-6) suppressed both sexual motivation and sexual performance.
摘要
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