Green Andrew E C, Causey Patrick W, Louie Anika S, Armstrong Andrea F, Harrington Laura E, Valliant John F
Departments of Chemistry and Medical Physics & Applied Radiation Sciences, McMaster University, 1280 Main Street West, Hamilton, Ontario, Canada L8S 4M1.
Inorg Chem. 2006 Jul 24;45(15):5727-9. doi: 10.1021/ic0605928.
Microwave heating was used to prepare eta5-rhenium carborane complexes in aqueous reaction media. For carboranes bearing sterically demanding substituents, isomerization of the cage from 3,1,2 to 2,1,8 derivatives occurred concomitantly with complexation. Microwave heating was equally effective at the tracer level using technetium-99m, affording access to a new class of synthons for designing novel molecular imaging agents.
在水相反应介质中，采用微波加热法制备了η5-铼碳硼烷配合物。对于带有空间位阻较大取代基的碳硼烷，在络合过程中同时发生了笼状结构从3,1,2异构体到2,1,8衍生物的异构化。在示踪剂水平上，使用锝-99m时微波加热同样有效，为设计新型分子成像剂提供了一类新的合成子。
