O'Riordan M, Kingston S, O'Regan P
St. Joseph's Hospital, Clonmel.
Ir J Med Sci. 1991 Jun;160(6):176-8. doi: 10.1007/BF02961667.
A prospective study of admissions to an Irish provincial coronary care unit in the light of reported benefits of streptokinase and oral aspirin as reported in the Isis study was carried out. Of 115 patients admitted with suspected myocardial infarction (M.I.), the diagnosis was confirmed in 41. The average delay from onset of chest pain to admission to C.C.U. was 6.65 hours (0.3-18 hours, median 6 hours). Twenty-six of the 41 patients were given streptokinase after a median time lapse of six hours from the onset of pain. 88% of the M.I. patients were on oral aspirin at discharge but only 12% were on oral beta blockers. These findings are compared with the findings of the Isis 2 study worldwide and in Ireland. The presence of risk factors in the patients with M.I. is analysed, 16 of the 41 had serum cholesterol levels greater than 6 mmols/l. As an index of community risk factor screening, an enquiry was made of the patients and of their family doctor as to whether serum cholesterol had previously been checked, this had been done in only 12 of 41 and in only 2 had it been carried out by the family doctor. Pre-hospital analgesic use was also examined and 36 of the 41 patients had chest pain and were seen by their G.P.s but only 18 were given analgesics of whom 13 received morphine.(ABSTRACT TRUNCATED AT 250 WORDS)
根据 ISIS 研究报告的链激酶和口服阿司匹林的益处，对爱尔兰一家省级冠心病监护病房的入院患者进行了一项前瞻性研究。在 115 名疑似心肌梗死（M.I.）入院的患者中，41 名确诊。从胸痛发作到入住冠心病监护病房的平均延迟时间为 6.65 小时（0.3 - 18 小时，中位数 6 小时）。41 名患者中有 26 名在疼痛发作后中位数 6 小时后接受了链激酶治疗。88%的心肌梗死患者出院时服用口服阿司匹林，但只有 12%服用口服β受体阻滞剂。这些结果与全球及爱尔兰的 ISIS 2 研究结果进行了比较。分析了心肌梗死患者的危险因素，41 名患者中有 16 名血清胆固醇水平高于 6 mmol/L。作为社区危险因素筛查的一项指标，对患者及其家庭医生进行了询问，了解血清胆固醇此前是否已检测，41 名患者中只有 12 名进行过检测，其中只有 2 名是由家庭医生检测的。还检查了院前镇痛药物的使用情况，41 名患者中有 36 名有胸痛并看过全科医生，但只有 18 名给予了镇痛药，其中 13 名接受了吗啡。（摘要截选至 250 字）
