Smith L H
J Thorac Cardiovasc Surg. 1975 Jul;70(1):147-51.
The neural crest origin of cells secreting amine and polypeptide hormones (APUD cells) is a unifying concept. The relationship of the classical endocrine system to that of tumor hormone secretion can be explained by the diffuse migration and later neoplasia of these unique cells. This paper describes the APUD cell origins of oat cell carcinoma.
分泌胺和多肽激素的细胞(APUD细胞)起源于神经嵴,这是一个统一的概念。经典内分泌系统与肿瘤激素分泌系统之间的关系可以通过这些独特细胞的广泛迁移及随后发生的肿瘤形成来解释。本文描述了燕麦细胞癌的APUD细胞起源。