结节性肥大细胞增多症。

Nodular mastocytosis.

作者信息

Kasprowicz Sarah, Chan I-Ja, Wall Daniel J, Tharp Michael D

机构信息

Department of Dermatology, Rush University Medical Center, Chicago, IL 60612, USA.

出版信息

J Am Acad Dermatol. 2006 Aug;55(2):347-9. doi: 10.1016/j.jaad.2005.11.1032.

DOI:10.1016/j.jaad.2005.11.1032

PMID:16844528

Abstract

Mastocytosis refers to a group of disorders characterized by the pathologic proliferation of mast cells. We present a 70-year-old white man with a rare presentation of nodular mastocytosis, characterized by disseminated nodular lesions, myelodysplastic syndrome, and a c-kit V560G receptor mutation. The patient presented to the clinic after initial presentation 6 months earlier, with ear pruritus, associated hearing loss, and widespread rash.

摘要

肥大细胞增多症是指一组以肥大细胞病理性增殖为特征的疾病。我们报告一名70岁白人男性，其表现为罕见的结节性肥大细胞增多症，特征为弥漫性结节性病变、骨髓增生异常综合征及c-kit V560G受体突变。该患者在6个月前首次就诊后再次前来门诊，伴有耳部瘙痒、相关听力丧失及广泛皮疹。