Butany Jagdish, Bahl Nina E, Morales Kathy, Thangaroopan Molly, Ross Heather, Rao Vivek, Leong Shaun W
Department of Pathology, Toronto General Hospital/University Health Network, Toronto, Canada.
Cardiovasc Pathol. 2006 Jul-Aug;15(4):222-7. doi: 10.1016/j.carpath.2006.02.005.
Primary cardiac sarcoidosis (CS) is rare, and concomitant involvement of the coronary arteries is rarer still. Successful diagnosis of this disease is difficult due to its nonspecific symptoms which mimic those of idiopathic dilated cardiomyopathy (IDCM).
We describe a 47-year-old Caucasian male who underwent orthotopic heart transplant for presumed IDCM. Examination of the explanted heart revealed numerous nonnecrotizing granulomata throughout, similar granulomata in the walls of the large coronary arteries, and large areas of fibrosis.
In cases of IDCM with symptoms of angina or acute coronary syndrome, the possibility of CS should be considered. Herein, we present this case and a review of the relevant literature.
原发性心脏结节病（CS）较为罕见，冠状动脉同时受累的情况更为罕见。由于该病症状不具特异性，与特发性扩张型心肌病（IDCM）相似，因此成功诊断较为困难。
我们描述了一名47岁的白种男性，因疑似IDCM接受了原位心脏移植。对切除的心脏进行检查发现，心脏各处有大量非坏死性肉芽肿，大冠状动脉壁有类似的肉芽肿，以及大面积纤维化。
对于有胸痛或急性冠状动脉综合征症状的IDCM病例，应考虑CS的可能性。在此，我们展示该病例并对相关文献进行综述。
