Hyland Christopher, Pinney John W, McConkey Glenn A, Westhead David R
Faculty of Biological Sciences, University of Leeds, Clarendon Way, Leeds LS2 9JT, UK.
Nucleic Acids Res. 2006 Jul 1;34(Web Server issue):W725-8. doi: 10.1093/nar/gkl196.
The metaSHARK (metabolic search and reconstruction kit) web server offers users an intuitive, fully interactive way to explore the KEGG metabolic network via a WWW browser. Metabolic reconstruction information for specific organisms, produced by our automated SHARKhunt tool or from other programs or genome annotations, may be uploaded to the website and overlaid on the generic network. Additional data from gene expression experiments can also be incorporated, allowing the visualization of differential gene expression in the context of the predicted metabolic network. metaSHARK is available at http://bioinformatics.leeds.ac.uk/shark/.
metaSHARK（代谢搜索与重建工具包）网络服务器为用户提供了一种直观、完全交互式的方式，可通过万维网浏览器探索KEGG代谢网络。由我们的自动化SHARKhunt工具或其他程序或基因组注释生成的特定生物体的代谢重建信息，可以上传到该网站并叠加在通用网络上。基因表达实验的其他数据也可以纳入，从而能够在预测的代谢网络背景下可视化差异基因表达。可通过http://bioinformatics.leeds.ac.uk/shark/访问metaSHARK。
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