角膜转运过程的数值模拟
Numerical simulation of corneal transport processes.
作者信息
Li Long-yuan, Tighe Brian
机构信息
School of Engineering and Applied Science, Aston University, Birmingham B4 7ET, UK.
出版信息
J R Soc Interface. 2006 Apr 22;3(7):303-10. doi: 10.1098/rsif.2005.0085.
Abstract
This paper presents a numerical study on the transport of ions and ionic solution in human corneas and the corresponding influences on corneal hydration. The transport equations for each ionic species and ionic solution within the corneal stroma are derived based on the transport processes developed for electrolytic solutions, whereas the transport across epithelial and endothelial membranes is modelled by using phenomenological equations derived from the thermodynamics of irreversible processes. Numerical examples are provided for both human and rabbit corneas, from which some important features are highlighted.
摘要
本文对离子和离子溶液在人角膜中的传输以及对角膜水合作用的相应影响进行了数值研究。基于针对电解质溶液发展的传输过程，推导了角膜基质内各离子种类和离子溶液的传输方程，而跨上皮和内皮膜的传输则通过使用从不可逆过程热力学推导的唯象方程进行建模。给出了人类和兔角膜的数值示例，并突出了一些重要特征。
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