[Study on quality standard of Yixin Tablet].

OBJECTIVE

T o determine the quality standard of Yixin Tablet.

METHODS

The nature differentiation of Radix Ginseng, Radix Astragali, Rhizoma Chuanxiong, Fructus Schisandrae was determined by TLC and content of salvianolic acid B in Yixin Tablet was determined by HPLC.

RESULTS

The nature differentiation separate degree is kind and special attribute was strong. The compounds were base-isolated on the column of C18 which gradient eluted with acetonitrile and H2O (0.05% H3PO4) and detective wavelength was 280 nm. The linearity was obtained over the range of 0.12504-2.50080 microg (r = 0.9999) and the average recovery rate was 99.35%.

CONCLUSION

The method is simple, convenient and accurate. The sensitivity is high. It can be used in the quality control of Yixin Tablet.