[丹莫胶囊质量标准研究]
[Study on the quality standard of danmo capsule].
作者信息
Li Rui-Ming, Chen Xiao, Lin Sheng-Wen, Long Ying, Cao Yuan, Wu Min-Jiang, Ren Bin
机构信息
Department of Pharmacy, The First Affiliated Hospital of Sun-Yat-Sen University, Guangzhou 510080, China.
出版信息
Zhong Yao Cai. 2011 Oct;34(10):1618-21.
OBJECTIVE
To establish the quality standard for Danmo capsule.
METHODS
TLC was used for the qualitative identification of Salviae Miltiorrhizae Radix Et Rhizoma and Lonicerae Japonicae Flos. HPLC was used to determine the content of Salvianolic acid B.
RESULT
TLC spots were clear and well-separated without negative interference. The linear range of Salvianolic acid B was 0.120042 - 2.40084 microg (r = 0.9999) with an average recovery of 103.63%, RSD was 0.6% (n = 6).
CONCLUSION
The method is simple, accurate and reliable. It can be used for the quality control of Danmo capsule.
目的
建立丹莫胶囊的质量标准。
方法
采用薄层色谱法（TLC）对丹参和金银花进行定性鉴别。采用高效液相色谱法（HPLC）测定丹酚酸B的含量。
结果
薄层色谱斑点清晰，分离良好，无阴性干扰。丹酚酸B的线性范围为0.120042 - 2.40084微克（r = 0.9999），平均回收率为103.63%，相对标准偏差为0.6%（n = 6）。
结论
该方法简便、准确、可靠。可用于丹莫胶囊的质量控制。
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