Christopherson W M, Mays E T, Barrows G H
Obstet Gynecol. 1975 Aug;46(2):221-3.
The possible association between oral contraceptives and benign liver tumors has recently been reported. To date the majority of cases have been diagnosed as benign hepatomas (liver cell adenomas). We have had the opportunity to study 13 such cases. Eight have been examples of focal nodular hyperplasia of the liver; however, in addition, there were examples of hepatocellular carcinoma, liver cell adenoma, and possible liver cell hamartoma; all were in women on "the pill." Gynecologists are alerted to the fact that many of the patients present with symptoms of acute abdomen, syncope or shock, and intrahepatic or intraperitoneal bleeding. Prompt diagnosis and treatment may be lifesaving.
最近有报道称口服避孕药与良性肝肿瘤之间可能存在关联。迄今为止，大多数病例被诊断为良性肝癌（肝细胞腺瘤）。我们有机会研究了13例此类病例。其中8例为肝脏局灶性结节性增生；然而，此外还有肝细胞癌、肝细胞腺瘤以及可能的肝细胞错构瘤病例；所有病例均为服用“避孕药”的女性。妇科医生应注意到许多患者表现出急腹症、晕厥或休克症状，以及肝内或腹腔内出血。及时诊断和治疗可能挽救生命。
