嗜热蛋白中芳香族簇的有利熵

Favorable entropy of aromatic clusters in thermophilic proteins.

作者信息

Trebbi Bruno, Dehez Francois, Fowler Patrick W, Zerbetto Francesco

机构信息

Dipartimento di Chimica G. Ciamician, Università di Bologna, via F. Selmi 2, 40126 Bologna, Italy.

出版信息

J Phys Chem B. 2005 Sep 29;109(38):18184-8. doi: 10.1021/jp052333u.

DOI:10.1021/jp052333u

PMID:16853335

Abstract

Aromatic clusters, found with increased frequency in a set of thermophilic proteins, confer an entropic advantage over mesophilic analogues through introduction of large-amplitude oscillations; this is a source of improved free energy at high temperatures.

摘要

在一组嗜热蛋白中发现的芳香族簇，通过引入大幅度振荡，比中温类似物具有熵优势；这是高温下自由能提高的一个来源。