[委内瑞拉马拉开波市一家大学医院血培养分离出的念珠菌属的抗真菌药敏概况]

[Profile of antifungal susceptibility of species of Candida isolated from hemocultures in a university hospital, Maracaibo, Venezuela].

作者信息

Arcaya Noris Margarita, Mesa Luz Mila, Pineda Maritza Rebeca, Beltrán-Luengo Haydee, Milagros Calvo Belinda

机构信息

Universidad Nacional Experimental Francisco de Miranda, Facultad de Medicina Departamento de Estudios Morfofuncionales, Coro, Estado Falcón, Venezuela.

出版信息

Rev Iberoam Micol. 2006 Jun;23(2):97-100. doi: 10.1016/s1130-1406(06)70022-5.

DOI:10.1016/s1130-1406(06)70022-5

PMID:16854186

Abstract

The aim of this study was to determine the in vitro susceptibility of amphotericin B, fluconazole and itraconazole, to several Candida spp recovered from blood cultures on hospitalized patients at the University Hospital of Maracaibo, Venezuela. The determination of the antifungal susceptibility was carried out according to the microdilution method in broth developed by The European Committee for Antimicrobial Susceptibility Testing (EUCAST). The profile of susceptibility of the 74 isolates showed that all the studied species were susceptible to amphotericin B, and 97.2% and 89.2% to fluconazole and itraconazole, respectively.

摘要

本研究的目的是确定两性霉素B、氟康唑和伊曲康唑对从委内瑞拉马拉开波大学医院住院患者血培养中分离出的几种念珠菌属的体外敏感性。抗真菌药敏试验按照欧洲抗菌药物敏感性试验委员会（EUCAST）制定的肉汤微量稀释法进行。74株分离菌的药敏谱显示，所有研究的菌种对两性霉素B敏感，对氟康唑和伊曲康唑的敏感率分别为97.2%和89.2%。