由对两性霉素B、伊曲康唑和氟康唑耐药的哈氏假丝酵母菌引起的新生儿真菌血症暴发。
Outbreak of fungemia among neonates caused by Candida haemulonii resistant to amphotericin B, itraconazole, and fluconazole.
作者信息
Khan Zia U, Al-Sweih Noura A, Ahmad Suhail, Al-Kazemi Nawal, Khan Seema, Joseph Leena, Chandy Rachel
机构信息
Department of Microbiology, Faculty of Medicine, Kuwait University, Safat 13110, Kuwait.
出版信息
J Clin Microbiol. 2007 Jun;45(6):2025-7. doi: 10.1128/JCM.00222-07. Epub 2007 Apr 11.
Abstract
The first outbreak of Candida haemulonii fungemia is described. The seven isolates from the blood of four neonates were identified by DNA sequencing of the ribosomal DNA. They were all resistant to amphotericin B, fluconazole, and itraconazole. This report highlights the emergence of C. haemulonii as an opportunistic pathogen in immunocompromised patients.
摘要
首次报道了哈氏假丝酵母菌血症的爆发。通过核糖体DNA的DNA测序鉴定了来自4名新生儿血液中的7株分离菌。它们对两性霉素B、氟康唑和伊曲康唑均耐药。本报告强调了哈氏假丝酵母菌作为免疫功能低下患者的机会性病原体的出现。
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