García-Arumí J, Martinez-Castillo V, Boixadera A, Fonollosa A, Corcostegui B
Hospital Vall d'Hebrón, Universidad Autónoma de Barcelona, Barcelona, Spain.
Br J Ophthalmol. 2006 Oct;90(10):1252-5. doi: 10.1136/bjo.2006.097642. Epub 2006 Jul 19.
To evaluate the anatomical outcomes, safety and functional effectiveness of surgical embolus removal in retinal artery occlusion (RAO).
Prospective study of seven patients with RAO of <36 h duration. All eyes underwent pars plana vitrectomy and a longitudinal incision of the anterior wall of the occluded arteriole in an attempt to remove the embolus. Outcome measures included visual acuity and arteriolar reperfusion, as evaluated with fluorescein angiography.
Surgical removal of the embolus was achieved in six of the seven (87.5%) patients, visual acuity improved from a median of 20/400 (range: hand movements 20/25) to 20/40 (range: hand movements 20/25), and reperfusion of the occluded vessel was angiographically confirmed in four of the six patients in whom the embolus was successfully removed.
Surgical removal of retinal arterial emboli seems to be an effective and safe treatment for RAO, but a randomised and controlled clinical trial will be necessary to establish an evidence base for the role, if any, of this intervention.
评估视网膜动脉阻塞(RAO)手术取栓的解剖学结果、安全性及功能有效性。
对7例病程小于36小时的RAO患者进行前瞻性研究。所有患眼均接受了玻璃体切除术及对阻塞小动脉前壁进行纵向切开,试图取出栓子。观察指标包括视力及通过荧光素血管造影评估的小动脉再灌注情况。
7例患者中有6例(87.5%)成功取出栓子,视力从中位数20/400(范围:手动 20/25)提高到20/40(范围:手动 20/25),在成功取出栓子的6例患者中,有4例经血管造影证实阻塞血管再灌注。
视网膜动脉栓子手术取出似乎是治疗RAO的一种有效且安全的方法,但需要进行随机对照临床试验,以建立该干预措施作用(若有)的循证基础。