Tunn P-U, Moesta T K, Delbrück H
Klinik für Chirurgie und Chirurgische Onkologie, Charité Campus Buch, Robert-Rössle-Klinik am Helios Klinikum Berlin, Lindenberger Weg 80, 13122 Berlin.
Chirurg. 2006 Oct;77(10):919-25. doi: 10.1007/s00104-006-1210-7.
Bilateral vascularized fibula graft (BVFG) is actually not a satisfying method for the replacement of metadiaphyseal defects of the femur and tibia in young patients suffering from malignant bone tumors. This reconstruction was used in five patients (two female, three male, average age 15.2 years, femur n=3, tibia n=2) undergoing metadiaphyseal resection of malignant bone tumors between November 2000 and August 2003. The median length of the defect to be bridged was 16.4 cm (range 11.5-23). In the two cases of tibia reconstruction, the ipsilateral fibula was transposed into the osseous defect (fibula pro tibia). The vessels of the contralateral fibula graft were microscopically anastomosed end-to-side upon the a. and v. tibialis anterior. For the reconstruction of femoral defects, two free fibula grafts were used. All patients had multimodal treatment according to the EURO-E.W.I.N.G 99 or COSS-96 protocol. Median follow-up was at 34 months. In all cases, R0 status was achieved. None of the patients experienced local recurrence during follow-up. Radiographic signs of osseous remodeling were detected the earliest after 2 months. Full weight-bearing on the affected leg was permitted after 8-18 months. Complications occurred in four patients (bleeding 1, infection and pseudarthrosis 1, fracture 1, plate fracture 1). None of the complications led to failure of the reconstruction or to amputation. The MSTS scores was very good in two patients, good in two, and intermediate in one. Biological reconstruction of osseous defects is always desirable when possible. Good functional and durable results can be obtained using BVFG for the reconstruction of metadiaphyseal defects of the femur and tibia.
双侧带血管腓骨移植术(BVFG)对于患有恶性骨肿瘤的年轻患者而言,实际上并非一种令人满意的用于替代股骨和胫骨干骺端缺损的方法。2000年11月至2003年8月期间,该重建方法应用于5例(2例女性,3例男性,平均年龄15.2岁,股骨3例,胫骨2例)接受恶性骨肿瘤干骺端切除术的患者。需桥接的缺损的中位长度为16.4厘米(范围11.5 - 23厘米)。在2例胫骨重建中,将同侧腓骨移位至骨缺损处(腓骨替代胫骨)。对侧腓骨移植的血管在显微镜下与胫前动脉和静脉进行端侧吻合。对于股骨缺损的重建,使用了两根游离腓骨移植。所有患者均根据EURO - E.W.I.N.G 99或COSS - 96方案接受多模式治疗。中位随访时间为34个月。所有病例均实现了R0状态。随访期间无患者出现局部复发。最早在2个月后检测到骨重塑的影像学迹象。8 - 18个月后允许患侧下肢完全负重。4例患者出现并发症(出血1例,感染和假关节1例,骨折1例,钢板骨折1例)。无一例并发症导致重建失败或截肢。2例患者的肌肉骨骼肿瘤协会(MSTS)评分非常好,2例良好,1例中等。只要有可能,骨缺损的生物重建总是可取的。使用BVFG重建股骨和胫骨干骺端缺损可获得良好的功能和持久的效果。