Mandelkow H, Halder P, Boesiger P, Brandeis D
Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland.
Neuroimage. 2006 Sep;32(3):1120-6. doi: 10.1016/j.neuroimage.2006.04.231. Epub 2006 Jul 24.
Investigating human brain function non-invasively by simultaneous EEG and fMRI measurements is gaining in popularity as more and better solutions to the inherent technical challenges emerge. We demonstrate the use of a commercially available frequency divider and phase-locking device for the purpose of synchronizing an MRI acquisition with a simultaneous recording of the EEG. Synchronization hugely improves the effectiveness of MRI artefact removal from the EEG signal by the common mean template subtraction method. It complements or substitutes post-processing techniques like filtering, thereby increasing the usable bandwidth of the EEG signal to about 150 Hz. This is important for covering the full range of human Gamma band activity. Similarly, synchronization eliminates the necessity for over-sampling of the EEG signal.
随着越来越多更好的方法来应对固有的技术挑战,通过同步脑电图(EEG)和功能磁共振成像(fMRI)测量来无创研究人类大脑功能正变得越来越流行。我们展示了使用一种商用分频器和锁相设备,目的是使MRI采集与EEG的同步记录同步。同步极大地提高了通过共同平均模板减法方法从EEG信号中去除MRI伪影的有效性。它补充或替代了诸如滤波等后处理技术,从而将EEG信号的可用带宽增加到约150Hz。这对于覆盖人类伽马波段活动的全范围很重要。同样,同步消除了对EEG信号过采样的必要性。