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随着新的药物治疗方法和选择性激光小梁成形术的引入,激光小梁成形术的发展趋势。

Laser trabeculoplasty trends with the introduction of new medical treatments and selective laser trabeculoplasty.

作者信息

Rachmiel Rony, Trope Graham E, Chipman Mary L, Gouws Peter, Buys Yvonne M

机构信息

Department of Ophthalmology and Visual Sciences, Toronto Western Hospital, Toronto, Ontario, Canada.

出版信息

J Glaucoma. 2006 Aug;15(4):306-9. doi: 10.1097/01.ijg.0000212233.11287.b3.

Abstract

PURPOSE

To correlate trends of laser trabeculoplasties (LTPs) with the introduction of medical therapies for glaucoma and to assess whether these trends changed after the introduction of selective laser trabeculoplasty (SLT) in 2001.

METHODS

A retrospective analysis of LTP numbers, filtration surgeries, glaucoma medications dispensed, and population distribution by age in Ontario, Canada, between April 1992 and March 2005.

RESULTS

The number of LTP per 1,000 persons estimated to have primary open angle glaucoma (POAG) increased from 138.05 in 1992 to a maximum of 149.23 in 1996 (8.1% increase, 1.96% annual increase) and then steadily decreased to 70.65 in 2001 (47.3% decrease, 14% annual decrease). From 2001 to 2004, the LTP rate increased to 162.54 (230% increase, 32% annual increase). The number of filtration surgeries per 1,000 persons estimated to have POAG steadily decreased from 1996 to 2004 by 21.42% (2.4% annual decrease). The number of glaucoma medications dispensed in Ontario increased from 1992 to 2004 by 91.5% (10.5% annual increase). There were no significant correlations between the LTP rates and the new glaucoma medications rates (r=-0.35 to 0.09; P=0.34 to 0.82) or filtration surgeries rates (r=0.007; P=0.98).

CONCLUSIONS

There was a substantial reduction in the number of LTP between 1997 and 2001 coinciding, but not correlated with the introduction of medications for the treatment of glaucoma. Between 2002 and 2004 the LTP rates increased, coinciding with the introduction of SLT.

摘要

目的

将激光小梁成形术(LTP)的趋势与青光眼药物治疗的引入相关联,并评估在2001年选择性激光小梁成形术(SLT)引入后这些趋势是否发生了变化。

方法

对1992年4月至2005年3月期间加拿大安大略省的LTP数量、滤过性手术、青光眼药物配给量以及按年龄划分的人口分布进行回顾性分析。

结果

每1000名估计患有原发性开角型青光眼(POAG)的人中LTP的数量从1992年的138.05增加到1996年的最高值149.23(增加8.1%,年增长率1.96%),然后稳步下降至2001年的70.65(下降47.3%,年下降率14%)。从2001年到2004年,LTP率增加到162.54(增加230%,年增长率32%)。每1000名估计患有POAG的人中滤过性手术的数量从1996年到2004年稳步下降了21.42%(年下降率2.4%)。安大略省青光眼药物的配给量从1992年到2004年增加了91.5%(年增长率10.5%)。LTP率与新的青光眼药物率(r = -0.35至0.09;P = 0.34至0.82)或滤过性手术率(r = 0.007;P = 0.98)之间无显著相关性。

结论

1997年至2001年间LTP数量大幅减少,这与青光眼治疗药物的引入同时发生,但两者并无关联。2002年至2004年间LTP率上升,这与SLT的引入同时发生。

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