Ríos Pedro J, Huaman Manuel, Ríos Pedro O
Servicio de Cirugía de Esófago-Estómago 3C II, Hospital E. Rebagliati M.
Rev Gastroenterol Peru. 2006 Apr-Jun;26(2):138-47.
Establishing the clinical pathological characteristics of adenocarcinomata of the esophagogastric junction of an insured population in our environment.
In this retrospective study, we studied sixty clinical histories of patients with a diagnosis of gastric adenocarcinomata, who had been surgically treated at the Edgardo Rebagliati Martins Hospital, 3C II Department of Surgery, EESALUD , Lima, Peru, from September 2002 to December 2004, and cases located at the esophagogastric junction (EGJ) were selected. Data were collected regarding: age, gender, presentation symptoms, anatomic location of the tumor, regional lymphatic metastasis (N), distance metastasis (M), TNM staging, excisability, complications, mortality and histological type.
Distribution according to anatomic location: 50% (30/60) were located at the esophagogastric junction, 23% (14/60) in the body and 27% (16/60) in the antrum. Of the 30 patients with adenocarcinomata of the EGJ, 80% (24/30) were male, 60% (18/30) were in their 60's or 70's and 47% (14/30) had upper gastrointestinal hemorrhage (UGIH). Type III tumors (subcardial) of the EGJ were found in 76% (23/30), in 63% (12/19) of the excised patients the serosa was affected, in 74% (14/19) the ganglia were affected and 83% (25/30) fell into stages III through IV. Excisions were performed on 63% (19/30), 42% (8/19) experienced complications, mortality was 10.5% (2/19) and in 67% (20/30) the histological type was clearly differentiated.
At our Hospital there seems to be an increase in the frequency of adenocarcinomata of the esophagogastric junction at the expense of other locations. Also, the subcardial type is more frequent than the cardial and distal esophagus types.
确定我们所在地区参保人群食管胃交界腺癌的临床病理特征。
在这项回顾性研究中,我们研究了2002年9月至2004年12月期间在秘鲁利马市EESALUD的埃德加多·雷巴利亚蒂·马丁斯医院3C II外科接受手术治疗的60例胃腺癌患者的临床病史,并选取了位于食管胃交界(EGJ)的病例。收集了以下数据:年龄、性别、临床表现症状、肿瘤的解剖位置、区域淋巴结转移(N)、远处转移(M)、TNM分期、可切除性、并发症、死亡率和组织学类型。
根据解剖位置分布:50%(30/60)位于食管胃交界,23%(14/60)位于胃体,27%(16/60)位于胃窦。在30例食管胃交界腺癌患者中,80%(24/30)为男性,60%(18/30)年龄在60或70多岁,47%(14/30)有上消化道出血(UGIH)。76%(23/30)的食管胃交界肿瘤为III型(贲门下型),63%(12/19)的切除患者浆膜受累,74%(14/19)的神经节受累,83%(25/30)处于III至IV期。63%(19/30)的患者进行了切除手术,42%(8/19)出现并发症,死亡率为10.5%(2/19),67%(20/30)的组织学类型为高分化。
在我们医院,食管胃交界腺癌的发病率似乎有所增加,而其他部位的发病率则有所下降。此外,贲门下型比贲门型和食管远端型更为常见。