Pascher Andreas, Klupp Jochen, Kohler Sven, Langrehr Jan-M, Neuhaus Peter
Department of Visceral and Transplantation Surgery, Charité-Universitätsmedizin Berlin, Campus Virchow Klinikum, Augustenburgerplatz 1, Berlin 13353, Germany.
World J Gastroenterol. 2006 Jul 21;12(27):4431-4. doi: 10.3748/wjg.v12.i27.4431.
To report an extended multivisceral transplantation (MVTx) including right kidney and ascending colon in a patient with complicated Crohn's disease (CD). A 36-year old female suffering from short bowel syndrome and frozen abdomen due to fistulizing CD after multiple abdominal operations underwent MVTx of eight organs including stomach, pancreatoduodenal complex, liver, intestine, ascending colon, right kidney, right adrenal gland, and greater omentum in November 2003. Immunosuppression consisted of alemtuzumab, tacrolimus and steroids. The patient was off parenteral nutrition by postoperative wk 3. She experienced one episode of pneumonia. The patient recovered completely and discharged 2.5 mo and was doing well 30 mo after MVTx. This is one of the very rare cases in which a complete mulitivisceral graft of eight abdominal organs was transplanted orthotopically.
报告1例复杂克罗恩病（CD）患者接受包括右肾和升结肠的扩大多脏器移植（MVTx）。1例36岁女性，因多次腹部手术后出现瘘管性CD导致短肠综合征和冰冻腹，于2003年11月接受了包括胃、胰十二指肠复合体、肝脏、小肠、升结肠、右肾、右肾上腺和大网膜在内的8个器官的MVTx。免疫抑制方案包括阿仑单抗、他克莫司和类固醇。术后第3周患者停止肠外营养。她经历了1次肺炎发作。患者完全康复，2.5个月后出院，MVTx后30个月情况良好。这是极罕见的原位移植8个腹部器官完整多脏器移植物的病例之一。
