Keshavarzi F, Salehi M, Mansouri A
Department of Radiology, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Department of Gynecology and Obstetrics, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran.
J Med Life. 2015;8(Spec Iss 3):54-58.
Uterine fibroma was a general gynecologic condition. When pharmacological therapies fail, surgical interferences such as myomectomy, hysterectomy, or embolization of uterine artery (UAE) are used as that state. This study aimed to compare hormone of anti-Mullerian measure among two methods of UAE, myomectomy into the treatment of uterine fibroma. In this clinical trial held in Imam Reza Hospital of Kermanshah, 40 cases by uterine fibroma were entered into the group of UAE (20 cases) and myomectomy (20 cases). Anti-Mullerian hormone levels were measured twice (ago and later therapeutic interventions) using the Monobinal kit. The information are examined by the SPSS (ver. 20.0) software by applying the Leven's test, paired and independent t-test, Wilcoxon, and Mann-Whitney tests. There is n't matter variation in terms of age between two groups (P> 0.05). Not important variation is recognized regarding anti-Mullerian hormone level before and after six months the medical intervention in either group (P> 0.05). Also, no important variation was detected among the 2 groups in terms of the anti-Mullerian hormone level (P= 0.58). The results obtained demonstrated that where is not statistically important variation among UAE and myomectomy by in terms of anti-Mullerian hormone, which reflects ovarian capacity. Therefore, UAE, which is a less invasive method, can be a suitable substitute for surgical methods in the therapy of significant uterine fibroids between women of the sexual period.
子宫纤维瘤是一种常见的妇科疾病。当药物治疗失败时，诸如肌瘤切除术、子宫切除术或子宫动脉栓塞术（UAE）等手术干预措施会被用于这种情况。本研究旨在比较两种UAE方法与肌瘤切除术治疗子宫纤维瘤时抗苗勒管激素的水平。在克尔曼沙赫伊玛目礼萨医院进行的这项临床试验中，40例子宫纤维瘤患者被纳入UAE组（20例）和肌瘤切除术组（20例）。使用Monobinal试剂盒两次测量抗苗勒管激素水平（治疗干预前后）。通过SPSS（版本20.0）软件应用Levene检验、配对和独立t检验、Wilcoxon检验以及Mann-Whitney检验对数据进行分析。两组之间在年龄方面没有显著差异（P>0.05）。在任何一组中，医疗干预六个月前后抗苗勒管激素水平方面均未发现显著差异（P>0.05）。此外，两组在抗苗勒管激素水平方面也未检测到显著差异（P = 0.58）。所获得的结果表明，在反映卵巢功能的抗苗勒管激素方面，UAE和肌瘤切除术之间没有统计学上的显著差异。因此，UAE这种侵入性较小的方法可以成为育龄期女性治疗大型子宫纤维瘤时手术方法的合适替代方案。
