Cirak Bayram, Kiymaz Nejmi, Arslanoglu Atilla
Department of Neurosurgery, Johns Hopkins Medical Institutions, Baltimore, MD, USA.
Pain Physician. 2004 Jan;7(1):129-32.
Trigeminal neuralgia (TGN) is characterized by recurrent paroxysms of unilateral facial pain that typically is severe, lancinating, and activated with cutaneous stimulation. Paroxysms typically last for 1 to 2 seconds. Etiology includes compression of the trigeminal nerve by vascular structures, tumors and multiple sclerosis plaques in the medulla spinalis. TGN is rather rare as a presenting symptom with intracranial tumors. Epidermoid tumors comprise 1% of all intracranial tumors. The majority of epidermoid tumors are located at the pontocerebellar angle, the third ventricle, and the suprasellar region. Symptomatology is not different from other tumors located at the same sites. Trigeminal neuralgia may be caused by tumor compressing the nerve itself, an inflammatory response to the epidermoid tumor or vascular compression of the nerve. We describe the case of a 30-year old female presenting with right-sided facial pain. Her past history revealed multiple teeth extractions done to relieve facial pain. Radiological evaluation, including magnetic resonance imaging (MRI), showed a pontocerebellar angle (PCA) epidermoid tumor. TGN resolved completely after total tumor resection. A temporary facial paralysis consequent to surgical removal of the tumor improved 6 months postoperatively, and she remained painfree, without medications.
三叉神经痛(TGN)的特征是单侧面部反复出现阵发性疼痛,通常较为剧烈,呈刀割样,且可因皮肤刺激而诱发。发作通常持续1至2秒。病因包括血管结构对三叉神经的压迫、肿瘤以及脊髓髓质中的多发性硬化斑块。TGN作为颅内肿瘤的首发症状较为罕见。表皮样肿瘤占所有颅内肿瘤的1%。大多数表皮样肿瘤位于桥小脑角、第三脑室和鞍上区域。其症状与位于相同部位的其他肿瘤并无差异。三叉神经痛可能由肿瘤压迫神经本身、对表皮样肿瘤的炎症反应或神经的血管压迫所致。我们报告一例30岁女性,表现为右侧面部疼痛。她的既往史显示曾多次拔牙以缓解面部疼痛。包括磁共振成像(MRI)在内的影像学评估显示为桥小脑角(PCA)表皮样肿瘤。肿瘤全切后三叉神经痛完全缓解。手术切除肿瘤后出现的暂时性面瘫在术后6个月有所改善,且她无需药物治疗,一直未再疼痛。