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老年慢性肾脏病患者的心血管疾病流行——同一问题的两个方面

The epidemics of cardiovascular disease in elderly patients with chronic kidney disease--two facets of the same problem.

作者信息

Covic Adrian, Gusbeth-Tatomir Paul, Goldsmith David J A

机构信息

Nephrology Clinic and Dialysis and Transplantation Center, C. I. PARHON University Hospital, 6600, Iasi, Romania.

出版信息

Int Urol Nephrol. 2006;38(2):371-9. doi: 10.1007/s11255-006-0044-z.

Abstract

There is increasing evidence that even mild renal dysfunction is a novel potent cardiovascular risk factor in the general elderly population. With more severe renal impairment, cardiovascular risk increases proportionately. This issue deserves attention, as chronic kidney disease (CKD) is predominantly a disease of the elderly, and the mean age of end-stage renal disease patients entering dialysis is growing constantly. In the dialysis population, when clinically significant cardiovascular disease (CVD) (particularly congestive heart failure) is present, survival is worse. Thus, every effort should be made to identify and treat cardiovascular risk factor in the early stages of CKD. However, elderly renal patients receive less proper cardiovascular therapy compared to non-renal subjects of the same age. This review deals briefly with the most significant data published in the last decade on CVD in elderly with CKD.

摘要

越来越多的证据表明,即使是轻度肾功能不全也是老年普通人群中一种新的强效心血管危险因素。随着肾功能损害加重,心血管风险也相应增加。这个问题值得关注,因为慢性肾脏病(CKD)主要是一种老年疾病,进入透析的终末期肾病患者的平均年龄在不断增长。在透析人群中,当存在具有临床意义的心血管疾病(CVD)(尤其是充血性心力衰竭)时,生存率更低。因此,应尽一切努力在CKD的早期阶段识别和治疗心血管危险因素。然而,与同龄的非肾病患者相比,老年肾病患者接受的心血管治疗不够恰当。本综述简要介绍了过去十年中发表的关于老年CKD患者CVD的最重要数据。

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