源自8-羟基喹啉的荧光汞离子选择性化学传感器。

Fluorogenic Hg2+-selective chemodosimeter derived from 8-hydroxyquinoline.

作者信息

Song Ki Cheol, Kim Jun Soo, Park Sang Mi, Chung Kee-Choo, Ahn Sangdoo, Chang Suk-Kyu

机构信息

Department of Chemistry, Chung-Ang University, Seoul 156-756, Korea.

出版信息

Org Lett. 2006 Aug 3;8(16):3413-6. doi: 10.1021/ol060788b.

DOI:10.1021/ol060788b

PMID:16869623

Abstract

[reaction: see text] A new thioamide derivative of 8-hydroxyquinoline-benzothiazole was prepared, and its fluorogenic chemodosimetric behaviors toward transition-metal ions were investigated. The thioamide derivative showed highly Hg2+-selective fluorescence enhancing properties (167-fold) in 30% aqueous acetonitrile solution. The selective and sensitive signaling behaviors were found to originate from the Hg2+ ion induced transformation of the very weak fluorescent thioamide derivative into a highly fluorescent amide analogue.

摘要

[反应：见正文] 制备了一种新型的8-羟基喹啉-苯并噻唑硫代酰胺衍生物，并研究了其对过渡金属离子的荧光化学计量行为。该硫代酰胺衍生物在30%乙腈水溶液中表现出对Hg2+具有高度选择性的荧光增强特性（167倍）。发现这种选择性和灵敏的信号行为源于Hg2+离子诱导极弱荧光的硫代酰胺衍生物转变为高荧光酰胺类似物。