一名全血细胞减少的HIV阴性、HHV-8阳性的多中心Castleman病患者经抗CD20治疗后完全缓解。
Complete remission in a pancytopenic HIV negative, HHV-8 positive patient with multicentric Castleman's disease induced with anti-CD20.
作者信息
Cervera Grau J M, Galiana Esquerdo G, Llorca Ferrándiz C, Briceño García H, Díaz Castellano M, Férriz Moreno P
机构信息
Oncology Department, Hospital General de Elda, Alicante, Spain.
出版信息
Clin Transl Oncol. 2006 Jul;8(7):540-1. doi: 10.1007/s12094-006-0056-2.
PMID:16870545
Abstract
A 75-year-old woman was diagnosed of MCD plasma cell (PC) variant with B symptoms. Diffuse lymph-node enlargement, splenomegaly and pancytopenia were detected. Induction with Rituximab was made because pancytopenia was present. Actually patient is free of disease. This is the first complete response of MCD published, VIH negative, induced with anti CD20.
摘要
一名75岁女性被诊断为伴有B症状的MCD浆细胞（PC）变异型。检测到弥漫性淋巴结肿大、脾肿大和全血细胞减少。由于存在全血细胞减少，采用利妥昔单抗进行诱导治疗。实际上患者目前无疾病。这是首例发表的用抗CD20诱导治疗且HIV阴性的MCD完全缓解病例。
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