Dicke Jeffrey M, Blanco Valerie M, Yan Yan, Coplen Douglas E
Division of Maternal-Fetal Medicine and Ultrasound, Department of Obstetrics and Gynecology, Washington University School of Medicine, St Louis, MO 63110, USA.
J Ultrasound Med. 2006 Aug;25(8):973-7. doi: 10.7863/jum.2006.25.8.973.
This study describes the frequency of sonographically detected fetal renal disorders, the correlation of fetal renal pelvis dilatation (RPD) with the need for postnatal surgery, and proposed management of RPD.
The study population consisted of 342 fetuses with prospectively identified isolated renal abnormalities and known follow-up. Fetuses with RPD were considered separately with respect to underlying renal disease, postnatal testing, and the need for surgical correction. Obstructive RPD was defined as the need for surgical treatment. Nonobstructive RPD included those cases that required no therapy. The correlation between prenatal RPD and the need for postnatal evaluation was examined.
Renal pelvis dilatation was the primary postnatal sonographic finding in 66.4% of cases. The remainder were distributed between multicystic dysplastic kidney, duplication malformations, and reflux, with a smaller number of other diagnoses. Renal pelvis dilatation in the obstructive group was significantly greater than in the nonobstructive group. However, 10% of fetuses with maximum RPD of 10 mm or less had an obstructive process, whereas 58% of fetuses with RPD of greater than 10 mm did not have obstruction. There were no cases in which preterm delivery was necessitated by RPD.
Renal pelvis dilatation is the most common fetal renal abnormality. The greater the RPD, the more likely it is due to obstruction. However, the overlap between obstruction and no obstruction dictates postnatal evaluation. In that RPD, regardless of degree, did not change the timing of delivery, a single follow-up sonographic examination either late in pregnancy or after delivery is considered adequate for follow-up of RPD detected earlier in pregnancy.
本研究描述了超声检测到的胎儿肾脏疾病的发生率、胎儿肾盂扩张(RPD)与出生后手术需求的相关性以及RPD的建议管理方法。
研究人群包括342例经前瞻性确定为孤立性肾脏异常且有已知随访结果的胎儿。对于有RPD的胎儿,分别就潜在肾脏疾病、出生后检查以及手术矫正需求进行了分析。梗阻性RPD定义为需要手术治疗的情况。非梗阻性RPD包括那些无需治疗的病例。研究了产前RPD与出生后评估需求之间的相关性。
肾盂扩张是66.4%病例出生后的主要超声检查发现。其余病例分布在多囊性发育不良肾、重复畸形和反流之间,其他诊断的病例较少。梗阻组的肾盂扩张明显大于非梗阻组。然而,最大RPD为10mm或更小的胎儿中有10%存在梗阻性病变,而RPD大于10mm的胎儿中有58%没有梗阻。没有因RPD而需要早产的病例。
肾盂扩张是最常见的胎儿肾脏异常。RPD越大,其由梗阻引起的可能性就越大。然而,梗阻与非梗阻之间的重叠情况决定了出生后需要进行评估。鉴于RPD无论程度如何都不会改变分娩时间,对于妊娠早期检测到的RPD,在妊娠晚期或分娩后进行一次超声随访检查被认为足以进行后续跟踪。