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香烟烟雾对成年白化大鼠体重、食物摄入量及生殖器官的影响。

Effect of cigarette smoke on body weight, food intake and reproductive organs in adult albino rats.

作者信息

Audi Sumedha S, Abraham Marjorie E, Borker Abhaya S

机构信息

Department of Physiology, Goa Medical College, Bambolim Goa, 403 202, India.

出版信息

Indian J Exp Biol. 2006 Jul;44(7):562-5.

Abstract

One hour daily exposure to cigarette smoke for two months significantly decreased the body weight and food intake in male and female albino rats. The latency for conception increased significantly and the litter size decreased. Mortality rate per litter increased and grayish discoloration of the skin in the experimental group was the only congenital anomaly seen. Testes and ovaries showed a significant decrease in weight. The stroma of the ovaries were occupied by very few Graafian follicles. Testes showed disruption of the normal orderly progression of the spermatogonia. The tubules showed only one layer of spermatogonia and very few germinal cells. The number of sperms was less in the testes. The results show that exposure to cigarette smoke is detrimental to the reproductivity in both, male and female albino rats.

摘要

每天暴露于香烟烟雾中一小时,持续两个月,显著降低了雄性和雌性白化大鼠的体重和食物摄入量。受孕潜伏期显著延长,产仔数减少。每窝的死亡率增加,实验组皮肤出现灰白色变色是唯一可见的先天性异常。睾丸和卵巢重量显著下降。卵巢基质中仅有极少数格拉夫卵泡。睾丸显示精原细胞正常有序进展受到破坏。曲细精管仅显示一层精原细胞,生殖细胞极少。睾丸中的精子数量较少。结果表明,暴露于香烟烟雾对雄性和雌性白化大鼠的生殖能力均有损害。

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