来自冲绳海洋海绵黄绿肉芝软珊瑚的倍半萜类化合物——海兔毒素A-D

Haterumadysins A-D, sesquiterpenes from the Okinawan marine sponge Dysidea chlorea.

作者信息

Ueda Katsuhiro, Kadekaru Takashi, Siwu Eric R O, Kita Masaki, Uemura Daisuke

机构信息

Department of Chemistry, Biology and Marine Sciences, University of the Ryukyus, Nishiharacho, Okinawa 903-0213, Japan.

出版信息

J Nat Prod. 2006 Jul;69(7):1077-9. doi: 10.1021/np058130e.

DOI:10.1021/np058130e

PMID:16872148

Abstract

Haterumadysins A-D (1-4) and two known compounds, spirodysin (5) and dehydroherbadysinolide (6), were isolated from the sponge Dysidea chlorea. Their structures were successfully determined by detailed spectroscopic analysis. Compounds 1-5 all showed the ability to inhibit the division of fertilized sea urchin eggs.

摘要

从海绵绿指海绵（Dysidea chlorea）中分离出了海特鲁马迪辛A-D（1-4）以及两种已知化合物，螺旋藻毒素（5）和脱氢海巴地辛内酯（6）。通过详细的光谱分析成功确定了它们的结构。化合物1-5均显示出抑制海胆受精卵分裂的能力。