Dallos Peter, Zheng Jing, Cheatham Mary Ann
Department of Neurobiology & Physiology, Northwestern University, 2240 Campus Drive, Evanston, IL 60208, USA.
J Physiol. 2006 Oct 1;576(Pt 1):37-42. doi: 10.1113/jphysiol.2006.114652. Epub 2006 Jul 27.
In non-mammalian, hair cell-bearing sense organs amplification is associated with mechano-electric transducer channels in the stereovilli (commonly called stereocilia). Because mammals possess differentiated outer hair cells (OHC), they also benefit from a novel electromotile process, powered by the motor protein, prestin. Here we consider new work pertaining to this protein and its potential role as the mammalian cochlear amplifier.
在非哺乳动物中,带有毛细胞的感觉器官放大作用与静纤毛(通常称为听毛)中的机械电换能通道有关。由于哺乳动物拥有分化的外毛细胞(OHC),它们还受益于一种由马达蛋白——预应力蛋白驱动的新型电运动过程。在此,我们探讨与该蛋白相关的新研究工作及其作为哺乳动物耳蜗放大器的潜在作用。