Andreola Carla, Ribeiro Maria P D, de Carli Carla R S, Gouvea Ana Luisa F, Curi André L L
Department of Ophthalmology, AIDS Section, Centro Previdenciário de Niterói, Rio de Janeiro, Brazil.
Am J Ophthalmol. 2006 Aug;142(2):346-8. doi: 10.1016/j.ajo.2006.03.024.
To report an uncommon case of multifocal choroiditis as the result of disseminated Cryptococcus neoformans infection in a patient who is HIV-positive.
Interventional case report.
A 27-year-old HIV-positive woman with fever, headache, and vomiting was examined. Lumbar puncture was performed and revealed C neoformans infection. Her condition evolved with sudden bilateral blindness and deafness. Ophthalmologic examination revealed multiple yellowish choroidal lesions in the posterior pole of both eyes.
Postmortem examination showed disseminated C neoformans infection. Histologic examination of the eyes confirmed the presence of C neoformans in the choroiditis.
Multifocal choroiditis in C neoformans infection is a rare ophthalmic manifestation. The recognition of this condition by ophthalmologists can help physicians to diagnose a disseminated and fatal disease.
报告一例因播散性新型隐球菌感染导致多灶性脉络膜炎的罕见病例，该患者为HIV阳性。
介入性病例报告。
对一名27岁发热、头痛和呕吐的HIV阳性女性进行检查。进行腰椎穿刺，结果显示新型隐球菌感染。她的病情发展为突然双侧失明和失聪。眼科检查发现双眼后极有多个淡黄色脉络膜病变。
尸检显示新型隐球菌播散性感染。眼部组织学检查证实脉络膜炎中存在新型隐球菌。
新型隐球菌感染中的多灶性脉络膜炎是一种罕见的眼科表现。眼科医生对这种情况的认识有助于医生诊断一种播散性致命疾病。
