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亚洲的出生结局差距。

The Asian birth outcome gap.

作者信息

Qin Cheng, Gould Jeffrey B

机构信息

School of Public Health, University of California, Berkeley, USA.

出版信息

Paediatr Perinat Epidemiol. 2006 Jul;20(4):279-89. doi: 10.1111/j.1365-3016.2006.00737.x.

Abstract

Asians are often considered a single group in epidemiological research. This study examines the extent of differences in maternal risks and birth outcomes for six Asian subgroups. Using linked birth/infant death certificate data from the State of California for the years 1992-97, we assessed maternal socio-economic risks and their effect on birthweight, preterm delivery (PTD), neonatal, post-neonatal and infant mortality for Filipino (87,120), Chinese (67,228), Vietnamese (45,237), Korean (23,431), Cambodian/Laotian (21,239) and Japanese (18,276) live singleton births. The analysis also included information about non-Hispanic whites and non-Hispanic blacks in order to give a sense of the magnitude of risks among Asians. Logistic regression models explored the effect of maternal risk factors and PTD on Asian subgroup differences in neonatal and post-neonatal mortality, using Japanese as the reference group. Across Asian subgroups, the differences ranged from 2.5- to 135-fold for maternal risks, and 2.2-fold for infant mortality rate. PTD was an important contributor to neonatal mortality differences. Maternal risk factors contributed to the disparities in post-neonatal mortality. Significant differences in perinatal health across Asian subgroups deserve ethnicity-specific interventions addressing PTD, teen pregnancy, maternal education, parity and access to prenatal care.

摘要

在流行病学研究中,亚洲人常被视为一个单一群体。本研究考察了六个亚洲亚群体在孕产妇风险和出生结局方面的差异程度。利用加利福尼亚州1992 - 1997年的出生/婴儿死亡证明关联数据,我们评估了菲律宾裔(87,120例)、华裔(67,228例)、越南裔(45,237例)、韩裔(23,431例)、柬埔寨/老挝裔(21,239例)和日裔(18,276例)单胎活产的孕产妇社会经济风险及其对出生体重、早产(PTD)、新生儿、新生儿后期和婴儿死亡率的影响。分析还纳入了非西班牙裔白人和非西班牙裔黑人的信息,以便了解亚洲人群体中风险的程度。逻辑回归模型以日本人为参照组,探讨了孕产妇风险因素和早产对亚洲亚群体新生儿和新生儿后期死亡率差异的影响。在亚洲各亚群体中,孕产妇风险差异范围为2.5至135倍,婴儿死亡率差异为2.2倍。早产是新生儿死亡率差异的一个重要因素。孕产妇风险因素导致了新生儿后期死亡率的差异。亚洲各亚群体围产期健康的显著差异值得针对早产、青少年怀孕、孕产妇教育、产次和获得产前护理等方面开展特定族裔的干预措施。

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