National Center for Child Health and Development, Tokyo, Japan.
Harvard School of Public Health, Boston, Massachusetts, USA.
Sci Rep. 2017 Apr 21;7:46657. doi: 10.1038/srep46657.
Though disparities in birth weight by race/ethnicity have been extensively reported in the United States, few studies have systematically investigated factors attributing to its variability. For 10,638,415 singleton infants born during 2009-2012 in the United States, we examined birth weight differences among 14 races and ethnicities (non-Hispanic white, non-Hispanic Black, American Indian, Asian Indian, Chinese, Filipino, Japanese, Korean, Vietnamese, Hawaiian, Guamanian, Mexican, Puerto Rican and Cuban), after sequentially adjusting for maternal, socio-economic and behavioral factors. Average birthweight of non-Hispanic white infants was 3381 g, while for other races/ethnicities birth weight ranged from being 289 g smaller in Japanese to 126 g larger in Samoan infants. Factors explaining differences of more than 50 grams in birth weight compared to white infants were: gestational age for black infants, height and body mass index for all Asian and Samoan mothers, and gestational weight gain for Japanese mothers. Difference in maternal age, parity, socioeconomic and behavioral characteristics did not account for significant portion of birthweight variations for any race. Our findings suggest that differences in maternal anthropometrics, gestational weight gain, and preterm birth rate, but not in maternal age, parity, socioeconomic or behavioral characteristics contribute to racial/ethnic differences in birthweight.
尽管在美国,不同种族/族裔之间的出生体重差异已经得到广泛报道,但很少有研究系统地调查导致这种差异的因素。我们对 2009 年至 2012 年期间在美国出生的 10638415 名单胎婴儿进行了研究,考察了 14 个种族/族裔(非西班牙裔白人、非西班牙裔黑人、美洲印第安人、印度裔、华裔、菲律宾裔、日裔、韩裔、越裔、夏威夷裔、关岛裔、墨西哥裔、波多黎各裔和古巴裔)之间的出生体重差异,这些差异是在依次调整了母亲、社会经济和行为因素后得出的。非西班牙裔白种婴儿的平均出生体重为 3381 克,而其他种族/族裔的出生体重范围从日裔婴儿的低 289 克到萨摩亚婴儿的高 126 克不等。与白种婴儿相比,解释出生体重差异超过 50 克的因素包括:黑人婴儿的胎龄、所有亚洲和萨摩亚母亲的身高和体重指数以及日本母亲的孕期体重增加。母亲年龄、产次、社会经济和行为特征的差异并不能解释任何种族出生体重变化的大部分原因。我们的研究结果表明,母亲的人体测量学、孕期体重增加和早产率的差异,但不是母亲的年龄、产次、社会经济或行为特征,导致了出生体重的种族/族裔差异。