Smith Richard D, Tang Keqi, Shen Yufeng
Biological Sciences Division, Pacific Northwest National Laboratory, P.O. Box 999, MS K8-98, Richland, WA 99352, USA.
Mol Biosyst. 2006 May;2(5):221-30. doi: 10.1039/b601468b. Epub 2006 Apr 6.
Electrospray ionization mass spectrometry combined with high efficiency capillary liquid chromatography provides high sensitivity and broad dynamic range measurements for the characterization of biological macromolecules in complex matrices, and is an increasingly powerful analytical tool for systems biology research.