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透视引导下的尾侧硬膜外类固醇注射对治疗慢性下腰痛有效吗?

Are fluoroscopic caudal epidural steroid injections effective for managing chronic low back pain?

作者信息

Southern Daniel, Lutz Gregory E, Cooper Grant, Barre Lisha

机构信息

Hospital for Spinal Surgery, Department of Physiatry, 535 East 70th St, New York, NY 10021, USA.

出版信息

Pain Physician. 2003 Apr;6(2):167-72.

Abstract

OBJECTIVE

This study sought to determine the efficacy of fluoroscopic caudal epidural steroid injections as a conservative treatment in patients with presumably chronic lumbar discogenic pain.

SUMMARY OF BACKGROUND DATA

Epidural steroid injections have been used in the treatment of lumbar radicular pain with success. However, despite their widespread use, there are few, if any, reports of the efficacy of Epidural steroid injections in patients with predominantly axial lumbar pain. Prior studies have been limited by the use of non-fluoroscopically guided injections and failing to apply a specific injection approach (i.e. transforaminal, interlaminar, or caudal) to a specific patient population.

METHODS

Ninety-seven patients with chronic axial low back pain and Magnetic Resonance Imaging evidence of disc pathology without stenosis were selected from chart review. All patients received at least one fluoroscopically guided caudal epidural injection with 12 mg of betamethasone and 8 cc of 0.5% lidocaine. Collected follow-up information included Roland-Morris Disability, Visual Numeric Pain Scale, and patient satisfaction scores.

RESULTS

Only nineteen patients (23%) were determined to have a successful long- term (> 1 year) outcome and 65 (77%) were deemed failures. Average follow-up was 28.6 +/- 15.6 months. Successes were found to differ significantly from failures in pre-injection pain scores and patient satisfaction. Overall patient satisfaction was 45%.

CONCLUSION

At greater than two year follow-up, the efficacy of fluoroscopically guided caudal epidural steroid injections in patients with chronic lumbar discogenic pain is poor. Patient satisfaction exceeds the reported rate of efficacy. Patients responding to injection have significantly lower pre-injection pain scores.

摘要

目的

本研究旨在确定透视引导下的骶管硬膜外类固醇注射作为保守治疗方法对疑似慢性腰椎间盘源性疼痛患者的疗效。

背景资料总结

硬膜外类固醇注射已成功用于治疗腰椎神经根性疼痛。然而,尽管其广泛应用,但关于硬膜外类固醇注射对以腰椎轴向疼痛为主的患者疗效的报道却很少。先前的研究受到非透视引导注射的使用限制,并且未能将特定的注射方法(即经椎间孔、椎板间或骶管)应用于特定的患者群体。

方法

通过病历回顾,从磁共振成像显示有椎间盘病变但无狭窄的患者中选取97例慢性轴向性下腰痛患者。所有患者均接受至少一次透视引导下的骶管硬膜外注射,注射药物为12毫克倍他米松和8毫升0.5%利多卡因。收集的随访信息包括罗兰-莫里斯功能障碍评分、视觉数字疼痛量表评分和患者满意度评分。

结果

仅19例患者(23%)被判定有成功的长期(>1年)疗效,65例(77%)被判定为治疗失败。平均随访时间为28.6±15.6个月。发现成功组与失败组在注射前疼痛评分和患者满意度方面存在显著差异。总体患者满意度为45%。

结论

在超过两年的随访中,透视引导下的骶管硬膜外类固醇注射对慢性腰椎间盘源性疼痛患者的疗效较差。患者满意度超过了报道的有效率。对注射有反应的患者注射前疼痛评分显著较低。

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