Lewis J D, Milbrath J R, Shaffer K A, Das Gupta T K
Arch Surg. 1975 Aug;110(8):903-7. doi: 10.1001/archsurg.1975.01360140047010.
Breast cancer screening, performed on asymptomatic women over 35 years of age, has identified 32 breast cancers in 30 of 4,500 women screened. Screening included a physical examination by trained technologists, thermography, and xeromammography. This represents 26 percent of the biopsies performed (116). Results of xerommammography were suspicious in 24 cases (80 percent), and results of physical examination were suspicious in 11 (37 percent). Only six were suspicious by both methods, with one other having changes that were considered benign. Fourteen (44 percent) were microinvasive or noninvasive. Only two (6 percent) had axillary metastases. Breast cancer detected by screening is in its "early" stages and is usually well localized. Operative management, including removal of the entire breast, has a significant potential for cure. Thirty patients with changes considered suspicious have not yet had biopsies. Improved overall survival depends on appropriate management of all patients screened.
对35岁以上无症状女性进行的乳腺癌筛查，在4500名接受筛查的女性中有30人查出了32例乳腺癌。筛查包括由训练有素的技术人员进行体格检查、热成像检查和干板乳腺摄影。这占活检病例的26%（116例）。干板乳腺摄影结果在24例（80%）中可疑，体格检查结果在11例（37%）中可疑。两种方法均可疑的只有6例，另有1例有被认为是良性的改变。14例（44%）为微浸润性或非浸润性。只有2例（6%）有腋窝转移。筛查发现的乳腺癌处于“早期”阶段，通常定位良好。手术治疗，包括切除整个乳房，有很大的治愈潜力。30例被认为有可疑改变的患者尚未进行活检。提高总体生存率取决于对所有接受筛查患者的适当管理。
