西印度群岛格林纳达孕妇和猫中弓形虫的血清流行率。

Seroprevalence of Toxoplasma gondii in pregnant women and cats in Grenada, West Indies.

作者信息

Asthana Sumita P, Macpherson Calum N L, Weiss Stanley H, Stephens Richard, Denny Thomas N, Sharma R N, Dubey J P

机构信息

Winward Islands Research and Education Foundation, Grenada, West Indies, St George's University, School of Medicine.

出版信息

J Parasitol. 2006 Jun;92(3):644-5. doi: 10.1645/GE-762R.1.

DOI:10.1645/GE-762R.1

PMID:16884013

Abstract

Prevalence of antibodies against Toxoplasma gondii was studied in 534 pregnant women and 40 domestic cats in Grenada, West Indies. Antibodies (IgG) for T. gondii were sought in human sera by an enzyme-linked immunosorbent assay and in cat sera by using the modified agglutination test (MAT). Antibodies were found in 57 % of pregnant women. Seroprevalence increased with age; 51% of 15- to 19-yr-old women (100 total) had antibodies versus 60% of 20- to 24-yr-old women (127 total). Antibodies to T. gondii (MAT, 1:25 serum dilution) were found in 35% of cats; titers were 1:25 in 7 cats, 1:50 in 4 cats, and 1:500 in 3 cats. Epidemiological data suggested that the ingestion of food or water contaminated with oocysts was an important mode of transmission of T. gondii to women.

摘要

在西印度群岛的格林纳达，对534名孕妇和40只家猫进行了抗弓形虫抗体流行率的研究。通过酶联免疫吸附测定法在人血清中检测弓形虫抗体（IgG），并使用改良凝集试验（MAT）在猫血清中检测。57%的孕妇检测到抗体。血清阳性率随年龄增长而升高；15至19岁的女性（共100人）中有51%检测到抗体，而20至24岁的女性（共127人）中有60%检测到抗体。35%的猫检测到抗弓形虫抗体（MAT，血清稀释度为1:25）；7只猫的滴度为1:25，4只猫的滴度为1:50，3只猫的滴度为1:500。流行病学数据表明，摄入被卵囊污染的食物或水是弓形虫向女性传播的重要途径。