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The lactic acid-induced acid tolerance response in Salmonella enterica serovar Typhimurium induces sensitivity to hydrogen peroxide.

作者信息

Greenacre E J, Lucchini S, Hinton J C D, Brocklehurst T F

机构信息

Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, United Kingdom.

出版信息

Appl Environ Microbiol. 2006 Aug;72(8):5623-5. doi: 10.1128/AEM.00538-06.

Abstract

Transcriptome analyses of Salmonella enterica serovar Typhimurium revealed that 15 genes were significantly up-regulated after 2 h of adaptation with lactic acid. cadB was the most highly up-regulated gene and was shown to be an essential component. Lactic acid-adapted cells exhibited sensitivity to hydrogen peroxide, likely due to down-regulation of the OxyR regulon.

摘要

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