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以腹部内脏肉芽肿形式表现的猫抓病。

Cat-scratch disease presenting as abdominal visceral granulomas.

作者信息

Delahoussaye P M, Osborne B M

机构信息

Department of Pathology and Laboratory Medicine, University of Texas Medical School, Houston.

出版信息

J Infect Dis. 1990 Jan;161(1):71-8. doi: 10.1093/infdis/161.1.71.

Abstract

Three cases of atypical, clinically unsuspected cat-scratch disease (CSD), diagnosed by demonstration of the CSD bacillus in an abdominal visceral organ, are presented. In two cases CSD bacilli were demonstrated for the first time in splenic granulomas in a child and in an adult with acquired immunodeficiency syndrome (AIDS)-related complex. In both cases, there was granulomatous hepatitis as well as splenitis. In the third case, the CSD bacillus was present in hepatic granulomas in an adult with granulomatous hepatitis. In all cases, granulomatous inflammation with suppuration in the viscera was identical to that previously described for lymph nodes in CSD. All patients eventually recovered completely. Clinical awareness of the broad spectrum of CSD should avoid the cost and morbidity of prolonged hospitalization, medications, and invasive surgery for a disease that is self-limited and not clearly responsive to antibiotics and that can usually be diagnosed by noninvasive means.

摘要

本文报告了三例非典型、临床未怀疑的猫抓病(CSD),通过在腹部内脏器官中证实存在CSD杆菌而确诊。其中两例中,首次在一名儿童和一名患有获得性免疫缺陷综合征(AIDS)相关综合征的成人的脾脏肉芽肿中发现了CSD杆菌。在这两例中,均存在肉芽肿性肝炎以及脾炎。第三例中,CSD杆菌存在于一名患有肉芽肿性肝炎的成人的肝脏肉芽肿中。在所有病例中,内脏器官中的肉芽肿性炎症伴化脓与先前描述的CSD淋巴结炎症相同。所有患者最终均完全康复。临床应认识到CSD临床表现的多样性,对于这种自限性疾病,且对抗生素无明显反应且通常可通过非侵入性手段诊断的疾病,应避免因长期住院、用药和侵入性手术带来的费用和发病率。

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