Rizk-Jackson Angela M, Acevedo Summer F, Inman Dean, Howieson Diane, Benice Theodore S, Raber Jacob
Department of Behavioral Neuroscience, L470, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, United States.
Behav Brain Res. 2006 Oct 16;173(2):181-90. doi: 10.1016/j.bbr.2006.06.029. Epub 2006 Aug 2.
Human tests designed to mirror rodent tests of object recognition and spatial navigation were administered to adult cognitively healthy humans. Facial recognition was also assessed. There was no sex difference in facial recognition, consistent with earlier studies. In the object recognition test, the test-retest NINL total scores during the same visit were highly correlated, comparable to the test-retest correlations obtained in the established facial recognition test. There were no effects of sex on object recognition. However, in the spatial navigation test, there were effects of sex on spatial learning and memory during the session with the hidden, but not visible, target. These tests might be useful to compare assessments of object recognition and spatial learning and memory in humans and animal models.
旨在模拟啮齿动物物体识别和空间导航测试的人体测试应用于认知健康的成年人。同时也评估了面部识别能力。面部识别方面不存在性别差异，这与早期研究一致。在物体识别测试中，同一次就诊期间的重测NINL总分高度相关，与既定面部识别测试中的重测相关性相当。性别对物体识别没有影响。然而，在空间导航测试中，在隐藏而非可见目标的测试环节中，性别对空间学习和记忆有影响。这些测试可能有助于比较人类和动物模型中物体识别以及空间学习和记忆的评估。
