Kassam Amin B, Mintz Arlan H, Gardner Paul A, Horowitz Michael B, Carrau Ricardo L, Snyderman Carl H
Department of Neurosurgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA.
Neurosurgery. 2006 Jul;59(1 Suppl 1):ONSE162-5; discussion ONSE162-5. doi: 10.1227/01.NEU.0000220047.25001.F8.
Aneurysms of the vertebral artery are rare, comprising less than 5% of all aneurysms. They can present with subarachnoid hemorrhage, medullary compression, and cranial neuropathies. In consideration of their surrounding regional anatomy, they present a formidable surgical challenge to the neurosurgeon using traditional techniques. Recent advances in endoscopic transnasal surgery have provided an additional approach for the treatment of these difficult lesions.
We present a case of a large vertebral artery aneurysm causing mass effect on the medulla. Initial treatment consisted of endovascular trapping of the aneurysm; however, because of concerns that the remaining aneurysm and intraluminal thrombus was causing mass effect and continued brainstem compression, a decompressive procedure was required.
After the endovascular trapping, the patient underwent a completely endoscopic transnasal surgical clipping and aneurysmorrhaphy. After exposure of the aneurysm, distal and proximal clips were applied transnasal, and the aneurysmorrhaphy completed using suction and ultrasonic aspiration.
In consideration of their surrounding regional anatomy, aneurysms of the vertebral artery present a formidable surgical challenge to the neurosurgeon. Although endovascular techniques have proven to be extremely valuable for the treatment of these lesions, they are limited when patients have significant mass effect with brainstem compression or cranial neuropathy. Advances in endoscopic transnasal surgery have provided an additional approach for the treatment of these difficult lesions. This case report represents, to our knowledge, the first literature report of a transnasal endoscopic aneurysm clipping and thrombectomy.
椎动脉动脉瘤较为罕见,占所有动脉瘤的比例不到5%。它们可表现为蛛网膜下腔出血、延髓受压和颅神经病变。鉴于其周围的局部解剖结构,使用传统技术对神经外科医生来说,对其进行手术具有极大的挑战性。鼻内镜手术的最新进展为治疗这些疑难病变提供了一种额外的方法。
我们报告一例大型椎动脉动脉瘤对延髓产生占位效应的病例。初始治疗包括对动脉瘤进行血管内栓塞;然而,由于担心残留的动脉瘤和腔内血栓会产生占位效应并持续压迫脑干,因此需要进行减压手术。
在血管内栓塞后,患者接受了完全经鼻内镜手术夹闭和动脉瘤缝合术。暴露动脉瘤后,经鼻应用远端和近端夹子,并用吸引器和超声吸引器完成动脉瘤缝合。
鉴于椎动脉动脉瘤周围的局部解剖结构,对神经外科医生来说,对其进行手术具有极大的挑战性。尽管血管内技术已被证明对治疗这些病变极具价值,但当患者出现明显的占位效应并伴有脑干压迫或颅神经病变时,这些技术存在局限性。鼻内镜手术的进展为治疗这些疑难病变提供了一种额外的方法。据我们所知,本病例报告是经鼻内镜动脉瘤夹闭和血栓切除术的首例文献报道。