Franceschini Emilie, Mensah Serge, Amy Dominique, Lefebvre Jean-Pierre
CNRS Laboratoire de Mécanique et d'Acoustique, 13402 Marseille 20, France.
IEEE Trans Ultrason Ferroelectr Freq Control. 2006 Jul;53(7):1281-8. doi: 10.1109/tuffc.2006.1665076.
Most breast cancers (85%) originate from the epithelium and develop first in the ductolobular structures. In screening procedures, the mammary epithelium should therefore be investigated first by the performing of an anatomically guided examination. For this purpose (mass screening, surgical guidance), we developed a two-dimensional anatomic phantom corresponding to an axial cross section of the ductolobular structures, which makes it possible to better understand the interactions between the breast composition and ultrasound. The various constitutive tissues were modeled as a random inhomogeneous continuum with density and sound speed fluctuations. Ultrasonic pulse propagation through the breast computer phantom was simulated using a finite element time domain method (the phantom can be used with other propagation codes). The simulated ductal echographic image is compared with the ductal tomographic (DT) reconstruction. The preliminary results obtained show that the DT method is more satisfactory in terms of both the contrast and the resolution.
大多数乳腺癌（85%）起源于上皮组织，首先在小叶结构中发展。因此，在筛查过程中，应首先通过进行解剖学引导检查来研究乳腺上皮组织。为此目的（大规模筛查、手术引导），我们开发了一种对应于小叶结构轴向横截面的二维解剖模型，这使得更好地理解乳腺成分与超声之间的相互作用成为可能。各种组成组织被建模为具有密度和声速波动的随机非均匀连续体。使用有限元时域方法模拟超声脉冲在乳腺计算机模型中的传播（该模型可与其他传播代码一起使用）。将模拟的导管超声图像与导管断层扫描（DT）重建结果进行比较。获得的初步结果表明，DT方法在对比度和分辨率方面都更令人满意。
